Marinalg Upholds Safety of Carrageenan

Long and safe history of use

Carrageenan is a unique and highly versatile food ingredient with a long history of safe use and broad global regulatory approvals for its use in foods and beverages. Carrageenan, which is derived from red seaweed, has been consumed for centuries and used in foods for over 600 years. Carrageenan offers numerous technological functions in foods and beverages and is commonly used to bind protein, promote gel formation, thicken, stabilize, and replace fat. The food additive is used in food and beverages, including processed food and beverages marketed as organic, and suitable in foods marketed as halal, kosher and vegan.

Evaluated by health authorities globally

Scientific and regulatory authorities from around the world have reviewed available scientific literature and safety data and have determined that carrageenan is safe for use in food. Carrageenan has been reviewed and approved by food safety authorities in the United States, the European Union, the Japan Ministry of Health, the Brazilian Health Surveillance ‎Agency, Health Canada, Food Standards Australia/New Zealand, the China Ministry of Health and ‎others. In July 2014, the Joint Expert Committee on Food Additives (JECFA)—an international expert scientific committee administered jointly by the Food and Agriculture Organization of the United Nations (FAO) and the World Health Organization (WHO)—also determined carrageenan is safe for use in all populations, including infants.

In connection to the general re-evaluation process of all approved food additives in the EU, the European Food Safety Authority (EFSA) published in April 2018 its Scientific Opinion on the re-evaluation of carrageenan and processed Eucheuma seaweed (PES) as food additives, evaluating new scientific data since the latest EU safety evaluation in 2003. In the Scientific Opinion, EFSA noted no safety concerns regarding carrageenan and processed Eucheuma seaweed (PES) but noted some uncertainties with supporting data. To fill these gaps, EFSA and the European Commission issued calls for technical and toxicological data on both carrageenan and PES in October 2018. There was no call for limitations in the use of carrageenan or PES nor did the authorities declare that either of these additives is unsafe for use in food.

Negative press in social media, not scientifically founded

Despite its long safety record, some have alleged that food-grade carrageenan causes harm to human health and called on food companies and retailers to replace carrageenan or not market products containing this important ingredient. Some of the alleged effects that have been mentioned are harmful interaction with the human gut microbiota, induction of intestinal inflammation and glucose intolerance, carcinogenicity and associations with chronic disease.

Most misunderstandings about the safety of carrageenan are a result ‎of misperception, misinterpreted research or a mischaracterization of the ingredient or degraded carrageenan (also called ‘poligeenan’) which is not permitted in food.1-4 Further, many of these are observational studies5-7 whichcannot and do not establish cause and effect and inherently have several weaknesses limiting the strength of their findings. ‎

Marinalg International is fully committed to food safety

Marinalg International, the global association representing manufacturers of seaweed-derived hydrocolloids, has since October 2018 been in dialogue with EFSA while preparing the necessary technical and toxicological data to address gaps and questions as identified by EFSA and the European Commission.  

Marinalg members are continuously involved in the development of safe and innovative food ingredients based on sound science. As such, Marinalg is committed to addressing all outstanding requests and continues to work with the Commission and EFSA. Thus, substantial data packages have already been submitted to EFSA in 2022, 2023, 2024 and 2025 and more is in preparation according to a project plan as agreed with EFSA. In the meantime, food manufacturers, retailers, and consumers can remain confident in the safety of carrageenan and processed Eucheuma seaweed.

Additional References:

  1. Borsani B, De Santis R, Perico V, Penagini F, Pendezza E, Dilillo D, Bosetti A, Zuccotti GV, D’Auria E. The Role of Carrageenan in Inflammatory Bowel Diseases and Allergic Reactions: Where Do We Stand? Nutrients. 2021; 13(10):3402. https://doi.org/10.3390/nu13103402
  2. Martino JV, Van Limbergen J, and Cahill LE. (2017) The Role of Carrageenan and Carboxymethylcellulose in the Development of Intestinal Inflammation. Frontiers Peds DOI=10.3389/fped.2017.00096
  3. Tobacman J.K. Review of harmful gastrointestinal effects of carrageenan in animal experiments. Environ. Health Perspect. 2001;109:983–994. doi: 10.1289/ehp.01109983
  4. Benard C., Cultrone A., Michel C., Rosales C., Segain J.-P., Lahaye M., Galmiche J.-P., Cherbut C., Blottière H.M. Degraded carrageenan causing colitis in rats induces TNF secretion and ICAM-1 upregulation in monocytes through NF-κB activation. PLoS ONE. 2010;5:e8666. doi: 10.1371/journal.pone.0008666
  5. Sellem L, Srour B, Javaux G, Chazelas E, Chassaing B, Viennois E, Debras C, Druesne-Pecollo N, Esseddik Y, Szabo de Edelenyi F, Arnault N, Agaësse C, De Sa A, Lutchia R, Huybrechts I, Scalbert A, Pierre F, Coumoul X, Julia C, Kesse-Guyot E, Allès B, Galan P, Hercberg S, Deschasaux-Tanguy M, Touvier M. Food additive emulsifiers and cancer risk: Results from the French prospective NutriNet-Santé cohort. PLoS Med. 2024 Feb 13;21(2):e1004338. doi: 10.1371/journal.pmed.1004338. PMID: 38349899; PMCID: PMC10863884.
  6. Sellem L, Srour B, Javaux G, Chazelas E, Chassaing B, Viennois E et al. Food additive emulsifiers and risk of cardiovascular disease in the NutriNet-Santé cohort: prospective cohort study BMJ 2023; 382 :e076058 doi:10.1136/bmj-2023-076058
  7. Payen de la Garanderie M, Hasenbohler A, Dechamp N, Javaux G, Szabo de Edelenyi F, Agaësse C, et al. (2025) Food additive mixtures and type 2 diabetes incidence: Results from the NutriNet-Santé prospective cohort. PLoS Med 22(4): e1004570. https://doi.org/10.1371/journal.pmed.1004570

April 2025

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